Phenidone 菲尼酮

CAS 92-43-3 MFCD00003094

化学结构图

92-43-3
SMILES: O=C1CCN(c2ccccc2)N1

化学属性

Mol. FormulaC9H10N2O
Mol. Weight162.19
Melting Point119-121°C
TSCAYes
Solubility溶于热水
Density1.188
Boiling Point288.88 °C at 760 mmHg

别名和识别编码

Chemical NamePhenidone
CAS Number92-43-3
Alfabeta NamePHENYLPYRAZOLIDINONE 13---
MDL NumberMFCD00003094
Synonym Phenidone {LY} Phenidone {} {LY} Phenidone {} {} {LY} Phenidone {} {} {} {LY} Phenidone {} {} {} {} {LY} Phenidone {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenidone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID87574404
EC Number202-155-1
Beilstein Registry Number131856
Merck Number7309
Reaxys-RN131856
Chemical Name Translation菲尼酮
Wiswesser Line NotationT5NMVTJ AR
LabNetwork Molecule IDLN00162246
Canonical SMILESO=C1NN(C2=CC=CC=C2)CC1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} Bioactive Small Molecules, Building Blocks, C9, Cell Biology, Chemical Synthesis, Heterocyclic Building Blocks, P, Pyrazoles
  • {SNA} Bioactive Small Molecules, Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, PA-PH, Pyrazoles, 细胞生物学
  • {SNA} Bioactive Small Molecules, Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, P, Pyrazoles, 细胞生物学
  • {SNA} Building Blocks, C9, Chemical Synthesis,

产品应用

  • 感光材料显影剂。

相关文献及参考

  • [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58.
  • [3]. Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16(12):1583-1587.
  • Merck: 14,7309
  • Merck: 14,7309 Beilstein:24,2
  • Short: EINECS
  • Short: IV/20C
  • [1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210.
  • [1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210.
  • [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive ag

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany2
Hazard statements
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H302 Harmful if swallowed 吞食有害
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECSUQ8750000
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P310+P330
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Packing GroupIII
UN Number 2811 UN 2811 6.1/PG 3
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R51/53
Hazard Codes 6.1 Xn,N Xn;N
Hazard Class6.1
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KODAK* Kodak Company Reports.  (343 State St., Rochester, NY 14650)
   Volume(issue)/page/year: 21MAY1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(1),49,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KODAK* Kodak Company Reports.  (343 State St., Rochester, NY 14650)
   Volume(issue)/page/year: 21MAY1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
RO

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1310 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(9)

Storage condition 2-8°C, sealed storage, away from moisture and light {LY} 2-8°C, sealed storage, away from moisture and light {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C

其他信息

  • 菲尼酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30145725 1-苯基-3-吡唑烷酮 50g 22元 2011/04/16 P0153 1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidone 500G 1990元 2011/04/16 P0153 1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidone 25G 233元
  • 图谱信息:菲尼酮(92-43-3)核磁图( 1 HNMR) 菲尼酮(92-43-3)核磁图( 13 CNMR) 菲尼酮(92-43-3)红外图谱(IR2) 菲尼酮(92-43-3)质谱(MS) 菲尼酮(92-43-3)红外图谱(IR3) 菲尼酮(92-43-3)红外图谱(IR1)
  • 溶于热水,极溶于稀酸和碱,溶于沸苯和醇,实际上不溶于醚和石油醚。
  • 用途二:感光材料显影剂。
  • MSDS 信息:1-Phenyl-3-pyrazolidinone(92-43-3).msds
  • 用途一:用作照相显影剂
  • MOL 文件:92-43-3.mol
  • Sigma Aldrich:92-43-3(sigmaaldrich)
  • TCI Shanghai:1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidone,>;98.0%(T)(92-43-3)
  • 上游原料:甲醇钠 --> 苯肼
  • Alfa Aesar:1-苯基-3-吡唑酮,97% 1-Phenyl-3-pyrazolidinone, 97%(92-43-3)
  • 外观性质:近似白色结晶。溶于热水,极溶于稀酸和碱,溶于沸苯和醇,实际上不溶于醚和石油醚。熔点:119-123 °C
  • 海关编码:29331990
  • Acros Organics:1-苯基-3-吡唑烷酮 1-Phenyl-3-pyrazolidinone, 97%(92-43-3)

系列性分类


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