Benzo[e]pyrene 苯并[e]芘

CAS 192-97-2 MFCD00003605

化学结构图

192-97-2
SMILES: c1ccc2c(c1)c1cccc3ccc4cccc2c4c31

化学属性

Mol. FormulaC20H12
Mol. Weight252.31
Melting Point177-180 °C
Flash Point-18 °C
Boiling Point495.49 °C at 760 mmHg

别名和识别编码

Chemical NameBenzo[E]Pyrene
Beilstein Registry Number1911334
PubChem Substance ID9128
MDL NumberMFCD00003605
EC Number205-892-7
CAS Number192-97-2
Synonym Benzo[e]pyrene {LY} Benzo[e]pyrene benzo(e)pyrene {} {LY} Benzo[e]pyrene {} {} {LY} Benzo[e]pyrene {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzo[e]pyrene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Chemical Name Translation苯并[e]芘
Merck Number13,1105
Wiswesser Line NotationL D6666 B6 2AB TJ
LabNetwork Molecule IDLN01275413
InChIInChI=1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H
Canonical SMILESC12=C3C(C=CC=C3)=C4C=CC=C5C=CC(C2=C45)=CC=C1
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分类

  • {uni_hamburg} no charge; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; 12ring; 14ring; 16ring; 18ring; 1fragment
  • {SNA} Arenes, Building Blocks, Chemical Synthesis, Light Emitters and Dopants, Materials Science, OLED and PLED Materials, Organic Building Blocks, Organic and Printed Electronics
  • {SNA} Arenes, Building Blocks, Chemical Synthesis, Light Emitters and Dopants, OLED and PLED Materials, Organic Building Blocks, Organic and Printed Electronics, 材料科学
  • A-B, All PAH Standards, Alpha Sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Aromatics, B,

相关文献及参考

  • Short: II/3
  • Short: III/5b
  • Merck: 14,1104 Beilstein: 5,IV,2689
  • Short: II/27C
  • Merck: 14,1104

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P308+P313
  • P318
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H350 May cause cancer 可能致癌
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Hazard Codes T,N F,Xn,N T,N,Xn,F
Signal word Danger
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSDJ4200000
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐:立即求医并出示该容器或标签;
Risk Statements
  • R11 Highly flammable 非常易燃
  • R45 May cause cancer 可能致癌
  • R38 Irritating to skin 刺激皮肤
  • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
  • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
  • R50/53
Packing GroupIII
Hazard Class6.1(b)
Storage condition APPROX 4°C 储存温度2-8℃
UN Number UN 3077 9/PG 3
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 140 mg/kg/37W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - facilitates action of known carcinogen
REFERENCE :
   AJCAA7 American Journal of Cancer.  (New York, NY)  V.15-40, 1931-40.  For
   publisher information, see CNREA8.  Volume(issue)/page/year: 27,474,1936

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg/43W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   VRRAAT Vestnik Rentgenologii i Radiologii.  Bulletin of Roentgenology and
   Radiology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1920-
   Volume(issue)/page/year: 20,276,1938

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   7,51,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - facilitates action of known carcinogen
REFERENCE :
   AJCAA7 American Journal of Cancer.  (New York, NY)  V.15-40, 1931-40.  For
   publisher information, see CNREA

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 100 mg/L
REFERENCE :
   MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road,
   Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-  Volume(issue)/page/year: 4,335,1989

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 192 umol/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 5,231,1984

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 1 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,2621,1978

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 10 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 368,59,1996

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6(Suppl
   2),1,1984

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 1 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 53,

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 150 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   SEIJBO Senten Ijo.  Congenital Anomalies.  (Nippon Senten Ijo Gakkai, c/o
   Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho,
   Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher
   information, see CGANE7.  Volume(issue)/page/year: 21,97,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 300 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   SEIJBO Senten Ijo.  Congenital Anomalies.  (Nippon Senten Ijo Gakkai, c/o
   Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho,
   Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher
   information, see CGANE7.  Volume(issue)/page/year: 21,97,1981

其他信息

  • 可燃性危险特性:可燃; 燃烧产生刺激烟雾
  • Sigma Aldrich:192-97-2(sigmaaldrich)
  • MOL 文件:192-97-2.mol
  • 苯并[E]芘价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 329750250 苯并[E]芘 Benzo[e]pyrene 90% 25 MG 1639元
  • 储运特性:通风低温干燥
  • Acros Organics:Benzo[e]pyrene, 99%(192-97-2)
  • 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
  • 类别:有毒物品

系列性分类


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