Galanthamine methiodide

CAS 3891-74-5 MFCD03891745

化学结构图

3891-74-5
SMILES: COc1ccc2c3c1OC1CC(O)C=CC31CC[N+](C)(C)C2.[I-]

化学属性

Mol. Weight429.33
Mol. FormulaC18H24NO3.I

别名和识别编码

Chemical NameGalanthamine methiodide
Synonym N-Methylgalanthaminium iodide Galanthamine iodomethylate Galanthamine methiodide Galanthaminium, 10-methyl-, iodide
CAS Number3891-74-5
InChIKeyBGQUXEGIISTLGG-PFYMQUAWSA-M
Chemical Name Translation
PubChem Substance ID199254
InChIInChI=1S/C18H24NO3.HI/c1-19(2)9-8-18-7-6-13(20)10-15(18)22-17-14(21-3)5-4-12(11-19)16(17)18;/h4-7,13,15,20H,8-11H2,1-3H3;1H/q+1;/p-1/t13-,15-,18?;/m0./s1
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安全信息

RTECSLW5957000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1320 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - fasciculations
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 25,168,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4250 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - fasciculations
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 25,168,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7100 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - fasciculations
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 25,168,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 98 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - fasciculations
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dys

系列性分类

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