4(3H)-Quinazolinone, 2-methyl-3-(2,5-xylyl)-

CAS 10367-31-4 MFCD00415981

化学结构图

10367-31-4
SMILES: CC1=CC(=C(C)C=C1)N1C(=O)C2C=CC=CC=2N=C1C

化学属性

Mol. FormulaC17H16N2O
Mol. Weight264.35

别名和识别编码

Chemical Name4(3H)-Quinazolinone, 2-methyl-3-(2,5-xylyl)-
Synonym Ro 326 2-Methyl-3-(2,5-xylyl)-4(3H)-quinazolinone 2-Methyl-3-(2',5'-dimethylphenyl)-4-chinazolinon 4(3H)-Quinazolinone, 3-(2,5-dimethylphenyl)-2-methyl-
CAS Number10367-31-4
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安全信息

RTECSVA4146600 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1200 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 22,129,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 710 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   17,616,1962

系列性分类

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