1-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl)Ethanol alpha-(2,4-二氯苯基)-1H-咪唑-1-乙醇

CAS 24155-42-8 MFCD00044708

化学结构图

24155-42-8
SMILES: OC(CN1C=NC=C1)C1C=CC(Cl)=CC=1Cl

化学属性

Mol. FormulaC11H10Cl2N2O
Mol. Weight257
Melting Point133-139
Solubility1300 G/L (20 ºC)

别名和识别编码

Chemical Name1-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl)Ethanol
CAS Number24155-42-8
Synonym (+/-)-?-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol 1-(2,4-Dichlorophenyl)-2-(1-imidazolyl)ethanol ?-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol Benzyl alcohol, 2,4-dichloro-alpha-(1-imidazolylmethyl)-
MDL NumberMFCD00044708
EC Number246-042-5
Reaxys-RN617090
Beilstein Registry Number617090
PubChem Substance ID87560113
Chemical Name Translationalpha-(2,4-二氯苯基)-1H-咪唑-1-乙醇
Wiswesser Line NotationT5N CNJ A1YQR BG DG
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分类

  • Pharmaceuticals
  • Heterocycles
  • Aromatics
  • Intermediates & Fine Chemicals
  • {SNA} Building Blocks, C9 to C30+, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Imidazoles

产品应用

  • Intermediate in the preparation of Miconazole.

相关文献及参考

  • Wahbi, Y., et al.: Eur. J. Med. Chem., 29, 701 (1994),

安全信息

Hazard Codes Xn
Safety Statements
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时,佩带适当的呼吸器;
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
RTECSNI5485000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,727,1981

WGK Germany3
GHS Symbol

系列性分类


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