(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid (S)-2-(丁基磺酰胺)-3-(4-(4-(哌啶-4-基)丁氧基)苯基)丙酸

CAS 144494-65-5 MFCD05237246

化学结构图

144494-65-5
SMILES: CCCCS(=O)(=O)N[C@@H](CC1C=CC(=CC=1)OCCCCC1CCNCC1)C(O)=O

化学属性

Mol. FormulaC22H36N2O5S
Mol. Weight440.60

别名和识别编码

Chemical Name(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid
Synonym (2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
MDL NumberMFCD05237246
Beilstein Registry Number6182267
Chemical Name Translation(S)-2-(丁基磺酰胺)-3-(4-(4-(哌啶-4-基)丁氧基)苯基)丙酸
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相关文献及参考

  • [2]. van 't Hof AW, Valgimigli M. Defining the role of platelet glycoprotein receptor inhibitors in STEMI: focus on tirofiban. Drugs. 2009;69(1):85-100.
  • [3]. Valgimigli M, Biondi-Zoccai G, Tebaldi M et al. Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials. Eur Heart J. 2010 Jan;31(1):35-49.
  • [4]. Valgimigli M, Tebaldi M. Safety evaluation of tirofiban. Expert Opin Drug Saf. 2010 Sep;9(5):801-19.
  • [5]. Diaz JF, Cardenal R, Gomez-Manchero A, Sanchez-Gonzalez C. Safety and efficacy of tirofiban as adjunctive therapy for patients with ST-elevation myocardial infarction: a comparison versus placebo and abciximab. Cardiovasc Hematol Agents Med Chem. 2011 Jul 1;9(3):147-53.
  • [1]. Winter JP, Juergens
  • [1]. Winter JP, Juergens CP. The role of tirofiban in the management of coronary artery disease. Cardiovasc Hematol Disord Drug Targets. 2008 Jun;8(2):138-46.

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSYP2364100
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

系列性分类

  1. Medical Research Areas
  2. Cytosketetal Signaling
  3. Integrin  (整合素)

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