Dichlorophenarsine hydrochloride

CAS 536-29-8 MFCD00536298

化学结构图

536-29-8
SMILES: Cl.Nc1cc([As](Cl)Cl)ccc1O

化学属性

Mol. Weight290.41
Mol. FormulaC6H6AsCl2NO.ClH

别名和识别编码

Wiswesser Line NotationZR BQ E-AS-GG &GH
Chemical NamePhenol, 2-amino-4-(dichloroarsino)-, hydrochloride
Synonym Arsine, (3-amino-4-hydroxyphenyl)dichloro-, hydrochloride R.P. 2591 Filarsen Spiropal Fontarsol 4000M Arsonous dichloride, (2-amino-4-hydroxyphenyl)-, monohydrochloride Dipharsine 3-Amino-4-hydroxyphenyl dichlorarsine hydrochloride Dichlorophenarsine hydrochloride 2591RP Chlorasene Arseclor (3-Amino-4-hydroxyphenyl)arsonous dichloride monohydrochloride Dichloromapharsen Chlorasen Halarsol Chlorarsol 2-Amino-4-(dichloroarsino)phenol hydrochloride Trepopal
CAS Number536-29-8
PubChem Substance ID68301
InChIInChI=1S/C6H6AsCl2NO.ClH/c8-7(9)4-1-2-6(11)5(10)3-4;/h1-3,11H,10H2;1H
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安全信息

RTECSSJ5775000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,12,1953

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 73,412,1941

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 957 ug/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - nausea or vomiting
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 73,412,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF E

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   9,626,1949

系列性分类

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