Benzamidine, 4,4'-oxydi-, dihydrochloride

CAS 5421-89-6 MFCD05421896

化学结构图

5421-89-6
SMILES: Cl.Cl.N=C(N)c1ccc(Oc2ccc(C(=N)N)cc2)cc1

化学属性

Mol. Weight327.24
Mol. FormulaC14H14N4O.2ClH

别名和识别编码

Wiswesser Line NotationMUYZR DOR DYZUM &GH 2
Chemical NameBenzamidine, 4,4'-oxydi-, dihydrochloride
Synonym 4,4'-Diamidino diphenyl ether dihydrochloride
CAS Number5421-89-6
InChIKeyCVVIOMFTTKEVJM-UHFFFAOYSA-N
PubChem Substance ID79460
InChIInChI=1S/C14H14N4O.2ClH/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18;;/h1-8H,(H3,15,16)(H3,17,18);2*1H
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安全信息

RTECSCV6300000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   ATMPA2 Annals of Tropical Medicine and Parasitology.  (Grune & Stratton,
   Inc., POB 6280, Duluth, MN 55806)  V.1-    1907-  Volume(issue)/page/year:
   37,1,1943

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   ATMPA2 Annals of Tropical Medicine and Parasitology.  (Grune & Stratton,
   Inc., POB 6280, Duluth, MN 55806)  V.1-    1907-  Volume(issue)/page/year:
   37,1,1943

系列性分类


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