N-Phenylmaleimide N-苯基马来酰亚胺

CAS 941-69-5 MFCD00005502

化学结构图

941-69-5
SMILES: O=C1C=CC(=O)N1c1ccccc1

化学属性

Mol. FormulaC10H7NO2
Mol. Weight173.17
Density1.422
Boiling Point162-163 °C at 12 mmHg
Melting Point85-87°C
TSCAYes
Flash Point152°C
Appearance 黄色针状结晶。熔点88-90℃。

别名和识别编码

Chemical NameN-Phenylmaleimide
Synonym N-Phenylmaleimide {LY} N-Phenylmaleimide N-phenylmaleimide {} {LY} N-Phenylmaleimide {} {} {LY} N-Phenylmaleimide {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Phenylmaleimide {} {} {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number941-69-5
EC Number213-382-0
Beilstein Registry Number125098
MDL NumberMFCD00005502
PubChem Substance ID13662
Merck Number7299
Alfabeta NamePHENYLDIHYDROPYRROLEDIONE H125125-------,,
Reaxys-RN125098
Chemical Name TranslationN-苯基马来酰亚胺
Wiswesser Line NotationT5VNVJ BR
LabNetwork Molecule IDLN00185743
InChIInChI=1S/C10H7NO2/c12-9-6-7-10(13)11(9)8-4-2-1-3-5-8/h1-7H
Canonical SMILESC2=C(N1C(C=CC1=O)=O)C=CC=C2
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分类

  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; 5ring; 6ring; amide; lactame; 1fragment
  • {SNA} Building Blocks, Carbonyl Compounds, Chemical Synthesis, Cyclic Imides, Organic Building Blocks

相关文献及参考

  • Short: III/35E
  • Used as a dipolarophile in 1,3-cycloaddition reaction with a nitrone, generated in situ: Org. Synth. Coll., 5, 957 (1973). Traps stereoselectively the small proportion of azomethine ylide in equilibrium with the imines of ɑ-amino acids: Tetrahedron, 44, 1523 (1988):
  • Short: EINECS
  • 1,3-Dipoles can also be generated by F- induced elimination: Org. Synth. Coll., 8, 231 (1993):
  • Dienophile useful for the preparation of crystalline adducts of dienes.

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P301+P310+P330
  • P301+P316
  • P302+P350
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P305+P354+P338
  • P307+P311
  • P308+P311
  • P308+P316
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P316
  • P317
  • P319
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P333+P313
  • P333+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H318 Causes serious eye damage 严重伤害眼睛
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H330 Fatal if inhaled 吸入致命
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECSON5950000
Packing GroupIII
UN Number UN 2811 6.1/PG 3
Hazard Codes T T,N T,Xi
Warnings IRRITANT
Hazard Class6.1
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,22,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 188 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCCUR* Shell Chemical Company.  Unpublished Report.  (2401 Crow Canyon Rd.,
   San Romon, CA 94583)  Volume(issue)/page/year: -,8,1961

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCCUR* Shell Chemical Company.  Unpublished Report.  (2401 Crow Canyon Rd.,
   San Romon, CA 94583)  Volume(issue)/page/year: -,8,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 78 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCCUR* Shell Chemical Company.  Unpublished Report.  (2401 Crow Canyon Rd.,
   San Romon, CA 94583)  Volume(issue)/page/year: -,8,1961

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 用途二:N-苯基马来酰亚胺(N-PMI)在天然橡胶和合成橡胶中可作为硫化交联剂,在ABS、PVC、PMMA树脂和感光材料中作为耐热改性剂,可提高树脂的耐热性,耐冲击性,热熔性和加工性等。N-PMI可用作树脂中间体,用来制造耐热聚合物,植物生长促进剂等农用化学品,N-PMI还有一定的抗菌活性。
  • TCI Shanghai:N-苯基马来酰亚胺 N-Phenylmaleimide,>;98.0%(GC)(941-69-5)
  • Acros Organics:N-苯基马来酰亚胺 N-Phenylmaleimide, 97%(941-69-5)
  • F:10-21
  • MOL 文件:941-69-5.mol
  • 用途一:主要用于提高树脂的耐热性,适用于制造涂料、粘合剂、感光性树脂、医药、农药等
  • MSDS 信息:1-Phenyl-1H-pyrrole-2,5-dione(941-69-5).msds
  • Alfa Aesar:N-苯基马来酰亚胺,98+% N-Phenylmaleimide, 98+%(941-69-5)
  • 制备方法:以马来酸酐为原料,与苯胺反应,可制得N-苯基马来酰亚胺。在反应的第一阶段生成酰胺酸,第二阶段要进行亚氨基化。以往在亚氨基化时,容易产生副反应而降低收率及纯度,现在采用催化法,避免了副反应,提高了收率和纯度。
  • N-苯基马来酰亚胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0900 N-苯基马来酰亚胺 N-Phenylmaleimide 500G 1500元 2014/06/02 P0900 N-苯基马来酰亚胺 N-Phenylmaleimide 25G 250元 2010/06/21 130711000 N-苯基马来酰亚胺 N-Phenylmaleimide 97% 100 GR 1731元
  • 图谱信息:N-苯基马来酰亚胺(941-69-5)红外图谱(IR2) N-苯基马来酰亚胺(941-69-5)红外图谱(IR1) N-苯基马来酰亚胺(941-69-5)核磁图( 1 HNMR) N-苯基马来酰亚胺(941-69-5)核磁图( 13 CNMR) N-苯基马来酰亚胺(941-69-5)质谱(MS)
  • 海关编码:29251995
  • Sigma Aldrich:941-69-5(sigmaaldrich)
  • 理化性质:从环己烷(或苯)中结晶者为浅黄色针状晶体。难溶于水、石油醚,溶于一般有机溶剂,特别易溶于丙酮、乙酸乙酯、苯。雄大鼠经口 LD50128mg/kg。
  • Hazard Note:Irritant

系列性分类


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