[Sp-4-2-(1R-Trans)]-(1,2-Cyclohexanediamine-N,N’) Dichloridoplatinum(II) (1,3-二氨基环己烷)二氯化铂

CAS 61848-66-6 MFCD00058826

化学结构图

61848-66-6
SMILES: Cl[Pt]Cl.N[C@@H]1CCCC[C@H]1N

化学属性

Mol. Weight380.21
Mol. FormulaC6H14Cl2N2Pt

别名和识别编码

InChIKeyPNNCIXRVXCLADM-UHFFFAOYSA-L
Chemical Name[Sp-4-2-(1R-Trans)]-(1,2-Cyclohexanediamine-N,N’) Dichloridoplatinum(II)
Synonym trans(-)-Dichloro-1,2-diaminocyclohexaneplatinum(II) trans(-)-Ddcp
CAS Number61848-66-6
Chemical Name Translation(1,3-二氨基环己烷)二氯化铂
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安全信息

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 41060 ug/kg/10W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,4368,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20530 ug/kg/10W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,4368,1981

RTECSTP2275980 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 nmol/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,4368,1981

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 13 umol/L/3H (Continuous)
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,4368,1981

系列性分类

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