11Beta-Hydroxyprogesterone

CAS 600-57-7 MFCD00064137

化学结构图

600-57-7
SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C

化学属性

Mol. FormulaC21H30O3
Mol. Weight330

别名和识别编码

Chemical Name11β-Hydroxy Progesterone
Synonym 11 alpha-hydroxyprogesterone 11 beta-hydroxy-4-pregnen-3,20-dione 11β-羟基-4-孕烯-3,20-二酮 11β-羟基孕-4-烯-3,20-二酮 4-孕烯-11β-醇-3,20-二酮 11-beta-Hydroxypregn-4-ene-3,20-dione 11-beta-Hydroxyprogesterone 11-hydroxyprogesterone 11-hydroxyprogesterone, (11alpha)-(+-)-isomer 11-hydroxyprogesterone, (11alpha)-isomer 11-hydroxyprogesterone, (11alpha,17alpha)-(+-)-isomer 11-hydroxyprogesterone, (11beta)-isomer 11-hydroxyprogesterone, (9beta,10alpha,11alpha)-isomer 11OHP compound 11beta-hydroxyprogesterone 21-Deoxycorticosterone Duralutin Gesterol Hy-Gestrone Hylutin Hyprogest Pergestron Pregn-4-ene-3,20-dione, 11-hydroxy-, (11-beta)- Pro-Depo Prodrox pregn-4-ene-11 beta-ol-3,20-dione
MDL NumberMFCD00064137
EC Number209-995-8
InChIKeyBFZHCUBIASXHPK-ATWVFEABSA-N
CAS Number600-57-7
LabNetwork Molecule IDLN01868411
PubChem Substance ID101788
InChIInChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18-,19+,20-,21+/m0/s1
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

相关文献及参考

  • [2]. Souness GW, et al. 11 alpha- and 11 beta-hydroxyprogesterone, potent inhibitors of 11 beta-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat. Hypertension. 1996 Mar;27(3 Pt 1):421-5.
  • [1]. Rafestin-Oblin ME, et al. 11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells. Mol Pharmacol. 2002 Dec;62(6):1306-13.
  • [1]. Rafestin-Oblin ME, et al. 11beta-hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells. Mol Pharmacol. 2002 Dec;62(6):1306-13.
  • [2]. Souness GW, et al. 11 alpha- and 11 beta-hydroxyprogesterone, potent inhibitors of 11 beta-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat. Hypertension. 1996 Mar;27(3 Pt 1):421-5.

安全信息

WGK Germany3
RTECSTU5058000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 28 mg/kg
SEX/DURATION            : female 28 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   JEMEAV Journal of Experimental Medicine.  (Rockefeller Univ. Press, 1230
   York Ave., New York, NY 10021)  V.1-    1896-  Volume(issue)/page/year:
   102,347,1955

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

相关产品推荐