(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate (S)-1-(2-乙基苯氧基)-3-(((S)-1,2,3,4-四氢萘-1-基)氨基)丙-2-醇草酸盐

CAS 174689-39-5 MFCD00940163

化学结构图

174689-39-5
SMILES: CCC1C=CC=CC=1OC[C@@H](O)CN[C@H]1CCCC2C=CC=CC=21.OC(=O)C(O)=O

化学属性

Mol. FormulaC21H27NO2· C2H2O4
Mol. Weight415.48

别名和识别编码

Chemical Name(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate
Synonym 3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt SR 59230A
MDL NumberMFCD00940163
PubChem Substance ID24278715
Chemical Name Translation(S)-1-(2-乙基苯氧基)-3-(((S)-1,2,3,4-四氢萘-1-基)氨基)丙-2-醇草酸盐
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分类

  • {SNA} Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Fluorination Ready Pharma-Developed Compounds, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmission (Obesity), Neurotransmitters, S, Sanofi Aventis, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 肥胖研究, 蛋白质及衍生物
  • {SNA} Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates,

相关文献及参考

  • [2]. Kanzler SA, et al. Involvement of β3-adrenergic receptors in the control of food intake in rats.Braz J Med Biol Res. 2011 Nov;44(11):1141-7.
  • [3]. Bruno G, et al. β3-adrenoreceptor blockade reduces tumor growth and increases neuronal differentiation in neuroblastoma via SK2/S1P2 modulation.Oncogene. 2020 Jan;39(2):368-384.
  • [4]. Bexis S, et al. Role of alpha 1- and beta 3-adrenoceptors in the modulation by SR59230A of the effects of MDMA on body temperature in the mouse. Br J Pharmacol. 2009 Sep;158(1):259-66.
  • [1]. Nisoli E, et al. Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.Mol Pharmacol. 1996 Jan;49(1):7-14.
  • [1]. Nisoli E, et al. Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.Mol Pharmacol. 1996 Jan;49(1):7-14.
  • [2]. Kanzler SA, et al. Involvement of β3-adrenergic receptors in the control of foo

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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