Antazoline mesylate

CAS 3131-32-6 MFCD00069668

化学结构图

3131-32-6
SMILES: CS(=O)(=O)O.c1ccc(CN(CC2=NCCN2)c2ccccc2)cc1

化学属性

Mol. FormulaC17H19N3.CH4O3S
Mol. Weight361.50

别名和识别编码

Chemical Name1H-Imidazole-2-methanamine,4,5-dihydro-N-phenyl-N-(phenylmethyl)-,monomethanesulfonate
Synonym 2-(N-苄基苯胺基甲基)-2-咪唑啉 Antazoline mesylate Antazoline methane sulphonate 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine Antistine methyl sulfonate Analergin Antazoline methanesulfonate
MDL NumberMFCD00069668
EC Number221-523-2
Wiswesser Line NotationT5M CN BUTJ B1NR&1R &OSW1
CAS Number3131-32-6
PubChem Substance ID222115
InChIInChI=1S/C17H19N3.CH4O3S/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);1H3,(H,2,3,4)
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安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P302+P352
  • P304+P312
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSNI6650000
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 144,887,1950

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 126 mg/L
REFERENCE :
   MSCREJ Medical Science Research.  (Elsevier Applied Science Pub. Ltd., Crown
   House, Linton Rd., Barking, Essex IG11 8JU, UK)  V.15-    1987-
   Volume(issue)/page/year: 18,735,1990

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 250 mg/L
REFERENCE :
   MSCREJ Medical Science Research.  (Elsevier Applied Science Pub. Ltd., Crown
   House, Linton Rd., Barking, Essex IG11 8JU, UK)  V.15-    1987-
   Volume(issue)/page/year: 18,735,1990

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