L-Prolinamide,L-tyrosyl-D-methionylglycyl-L-phenylalanyl-

CAS 63307-63-1 MFCD00076429

化学结构图

63307-63-1
SMILES: CSCC[C@@H](NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)NCC(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N1CCC[C@H]1C(N)=O

化学属性

Mol. FormulaC30H40N6O6S
Mol. Weight612.82

别名和识别编码

Chemical NameL-Prolinamide,L-tyrosyl-D-methionylglycyl-L-phenylalanyl-
Synonym GYKI 14238 D-Met(sup 2)pro(sup 5)-enkephalinamide
CAS Number63307-63-1
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安全信息

RTECSTW3583000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1700 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Behavioral - antipsychotic
   Behavioral - alteration of classical conditioning
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   39,641,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 118 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Behavioral - antipsychotic
   Behavioral - alteration of classical conditioning
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   39,641,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 510 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Behavioral - antipsychotic
   Behavioral - alteration of classical conditioning
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   39,641,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 278 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Behavioral - antipsychotic
   Behavioral - alteration of classical conditioning
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 10

系列性分类

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