OBIDOXIME

CAS 7683-36-5 MFCD07683365

化学结构图

7683-36-5
SMILES: O/N=C/c1cc[n+](COC[n+]2ccc(/C=N/O)cc2)cc1

化学属性

Mol. Weight288.34
Mol. FormulaC14H16N4O3

别名和识别编码

Chemical NamePyridinium, 1,1'-(oxydimethylene)bis(4-formyl-,dioxime
Chemicalbook IDCB41424795
Wiswesser Line NotationT6KJ D1UNQ A1O1- AT6KJ D1UNQ
Synonym Toxogonin Obidoxim Obidoxime tablets Obidoxime
CAS Number7683-36-5
PubChem Substance ID135412781
InChIInChI=1S/C14H14N4O3/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20/h1-10H,11-12H2/p+2
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安全信息

RTECSUU6850000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 203 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   46,429,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - paresthesis
   Behavioral - muscle weakness
   Gastrointestinal - nausea or vomiting
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   36,83,1976

系列性分类


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