3,4-Difluoroaniline 3,4-二氟苯胺

CAS 3863-11-4 MFCD00007761

化学结构图

3863-11-4
SMILES: Nc1ccc(F)c(F)c1

化学属性

Mol. FormulaC6H5F2N
Mol. Weight129.11
Boiling Point205°C at 760 mmHg
Density1.302
Refractive indexn20/D 1.513(lit.)
Flash Point85°C
TSCANo
Melting Point22°C
Solubility略溶于水
Appearance 无色至淡黄色透明液体。沸点77℃(7mmHg),闪点85℃,折光率1.5130,比重1.302。
pH:A

别名和识别编码

Chemical Name3,4-Difluoroaniline
CAS Number3863-11-4
Alfabeta NameDIFLUOROANILINE 34-,
MDL NumberMFCD00007761
EC Number223-381-7
Beilstein Registry Number971235
PubChem Substance ID87568278
Synonym 3,4-Difluoroaniline {LY} 3,4-Difluoroaniline {} {LY} 3,4-Difluoroaniline {} {} {LY} 3,4-Difluoroaniline {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Difluoroaniline {} {} {} {} {} {} {} {} {} {}
Reaxys-RN971235
Chemical Name Translation3,4-二氟苯胺
InChIKeyAXNUZKSSQHTNPZ-UHFFFAOYSA-N
LabNetwork Molecule IDLN00142431
InChIInChI=1S/C6H5F2N/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2
Canonical SMILESNC1=CC=C(F)C(F)=C1
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分类

  • {SNA} Amines, Aryl Fluorinated Building Blocks, Building Blocks, C6, Chemical Synthesis, Fluorinated Building Blocks, Nitrogen Compounds, Organic Building Blocks, Organic Fluorinated Building Blocks, Other Fluorinated Organic Building Blocks

安全信息

Warnings IRRITANT, TOXIC
Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R33 Danger of cumulative effects 有累积作用的危险
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P352+P332+P313+P362+P364
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H302+H332
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSCX9871900
Packing GroupIII
UN Number
Hazard Codes Xn Xn,Xi
Hazard Class6.1
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (3),31,1993

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10720 mg/m3
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (3),31,1993

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (3),31,1993

Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 检测方法:GC
  • 用途一:用作医药中间体
  • Acros Organics:3,4-二氟苯胺 3,4-Difluoroaniline, 99+%(3863-11-4)
  • Sigma Aldrich:3863-11-4(sigmaaldrich)
  • MOL 文件:3863-11-4.mol
  • Hazard Note:Irritant
  • Alfa Aesar:3,4-二氟苯胺,98+% 3,4-Difluoroaniline, 98+%(3863-11-4)
  • 3,4-二氟苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010074 3,4-二氟苯胺 5g 150元 2011/04/16 D1809 3,4-二氟苯胺 3,4-Difluoroaniline 25G 851元 2010/06/21 243190100 3,4-二氟苯胺 3,4-Difluoroaniline 99+% 10 ML 507元
  • F:8-10-23
  • 上游原料:铁粉
  • TCI Shanghai:3,4-二氟苯胺 3,4-Difluoroaniline,>;97.0%(GC)(3863-11-4)

系列性分类