(S)-4-Ethyl-4-Hydroxy-11-(2-(Isopropylamino)Ethyl)-1H-Pyrano[3',4':6,7]Indolizino[1,2-B]Quinoline-3,14(4H,12H)-Dione Hydrochloride (S)-4-乙基-4-羟基-11-(2-(异丙基氨基)乙基)-1H-吡喃并[3',4':6,7]吲哚并[1-2,b]喹啉-3,14((4H,12H)-二酮盐酸盐

CAS 213819-48-8 MFCD07772313

化学结构图

213819-48-8
SMILES: Cl.CC[C@]1(O)C2C=C3C4N=C5C=CC=CC5=C(CCNC(C)C)C=4CN3C(=O)C=2COC1=O

化学属性

Mol. FormulaC25H28ClN3O4
Mol. Weight469.96

别名和识别编码

Chemical Name(S)-4-Ethyl-4-Hydroxy-11-(2-(Isopropylamino)Ethyl)-1H-Pyrano[3',4':6,7]Indolizino[1,2-B]Quinoline-3,14(4H,12H)-Dione Hydrochloride
CAS Number213819-48-8
Synonym (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Hydrochloride CKD 602
Chemical Name Translation(S)-4-乙基-4-羟基-11-(2-(异丙基氨基)乙基)-1H-吡喃并[3',4':6,7]吲哚并[1-2,b]喹啉-3,14((4H,12H)-二酮盐酸盐
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分类

  • Amines
  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A novel camptothecin-derivative anti-tumor agent. CKD-602-related toxicities induced by IV infusion administration have not yet been evaluated, although the drug is more widely used in clinical settin

相关文献及参考

  • Hertzberg, R., et al.: J. Med. Chem., 32, 715 (1989),
  • Hashimoto, H., et al.: Clin. Cancer Res., 1, 369 (19950, Dahut, W., et al.: J. Clin. Oncol., 14, 1236 (1996),

系列性分类

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