Cytidine 5'-monophosphate disodium salt 胞苷 5'-磷酸二钠盐

CAS 6757-06-8 MFCD00064355

化学结构图

6757-06-8
SMILES: Nc1ccn([C@@H]2O[C@H](COP(=O)([O-])[O-])[C@@H](O)[C@H]2O)c(=O)n1.[Na+].[Na+]

化学属性

Mol. FormulaC9H12N3Na2O8P
Mol. Weight367.16
Density2.15
Melting Point300°C
TSCANo
Appearance crystalline 天然品存在于人乳等中。 无色至白色结晶或白色结晶性粉末，有特殊味道。溶于水(67%，20℃)，几乎不溶于乙醇等有机溶剂。0。01mol/L盐酸溶液的最大吸收光谱为279nm±2nm。加热至50℃开始释出结晶水，至185℃呈褐色，至260℃分解。
Refractive index8 ° (C=2, H2O)

别名和识别编码

Chemical NameCytidine 5'-monophosphate disodium salt
CAS Number6757-06-8
EC Number229-819-3
Beilstein Registry Number3582735
MDL NumberMFCD00064355
Synonym Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {} {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {} {} {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {} {} {} {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {} {} {} {} {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {} {} {} {} {} {LY} Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate {} {} {} {} {}
PubChem Substance ID94332
Reaxys-RN3582735
Chemical Name Translation胞苷 5'-磷酸二钠盐
LabNetwork Molecule IDLN00189506
InChIInChI=1S/C9H14N3O8P.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1
Canonical SMILESO[C@H]1[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1COP([O-])([O-])=O.[Na+].[Na+]
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分类

  • {Chemicalbook} 食品添加剂: 调味剂（风味增强剂）: 调味剂
  • {SNA} Nucleotide Analogs, 核苷，核苷酸和寡核苷酸, 生化试剂
  • {SNA} Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotide Analogs

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 图谱信息:胞苷 5'-磷酸二钠盐(6757-06-8)核磁图( 13 CNMR) 胞苷 5'-磷酸二钠盐(6757-06-8)核磁图( 1 HNMR) 胞苷 5'-磷酸二钠盐(6757-06-8)红外图谱(IR1)
  • 方法一:由酵母菌菌体制取核酸后，再经酶解、单离而得。
  • 用途一:调味剂。亦用于补充牛乳中的核苷酸，以生产接近人乳的母乳化牛奶，能增强婴儿对细菌性疾病的抵抗能力，加入量0.0015%。
  • 上游原料:核酸
  • 参考质量标准:日本标准，1999 含量 97%～102% 溶液性状 5%水溶液应为无色透明 5%水溶液的pH值 8.0～9.5 砷(以As2O3计，GT-3) ≤4mg/kg 重金属(以Pb计) ≤20mg/kg 吸光比(设在波长250、260、280nm处的吸光度分别为A1、A2、A3) A1/A2=0.4～0.52； A3 A2=1.85～2.2 其他核酸分解物试验 正常 水分(GT-32-1) ≤26.0%
  • TCI Shanghai:5'-单磷酸胞啶二钠盐 Cytidine-5'-monophosphate Disodium Salt,>;99.0%(LC)(6757-06-8)
  • F:1-10
  • MOL 文件:6757-06-8.mol
  • Sigma Aldrich:6757-06-8(sigmaaldrich)
  • 胞苷 5'-磷酸二钠盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0524 胞苷-5'-单磷酸二钠盐 Cytidine 5'-Monophosphate Disodium Salt Hydrate 5G 1100元 2014/06/02 C0524 胞苷-5'-单磷酸二钠盐 Cytidine 5'-Monophosphate Disodium Salt Hydrate 1G 327元
  • 鉴别试验:取试样20mg，溶于0.01mol/L盐酸100ml中。取该液10ml，加0.01mol/L盐酸至100ml，此液在279nm土2nm处有最大吸收峰。 取0.03%试样水溶液3ml，加盐酸1ml及溴试液(TS-46)1ml，于水浴中加热30min，吹入空气除溴，加10%苔黑酚乙醇液0.2ml，及硫酸铁铵盐酸试液(TS-100)3ml，于水浴中加热20min，应呈绿色。 取5%试样水溶液5ml，加镁氧混合剂试液(TS-133)2ml，应无沉淀发生。再加硝酸7ml，煮沸10min后，加氢氧化钠试液(TS-224)中和后，该液的磷酸盐试验应呈阳性(IT-26)。 试样的钠盐试验应呈阳性(IT-28)。
  • 含量分析:准确取称试样约500mg，用0.01mol/L盐酸液溶解并定容至1000ml。取该液10ml，加0.01mol/L盐酸液定容至250ml，以此作为试样液。以0.01mol/L盐酸液作为空白液。用1cm比色池在波长280nm处测定吸光度(A)，再按下式求出胞苷酸二钠的含量(%)： 胞苷酸二钠含量(%)=500/试样量（mg）×144.6×A/[100-水分（%）×100
  • 毒性:LD 50 ＞10g/kg(小鼠，经口)。 ADI不作特殊规定(FAO/WHO，1994)。

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleoside Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleosides - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleotide Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleotides - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Synthetic Oligonucleotides and Related Reagents - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. DNA / RNA Synthesis

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