N,N-Diethyl-p-Phenylenediamine N,N-二乙基对苯二胺

CAS 93-05-0 MFCD00007861

化学结构图

93-05-0
SMILES: CCN(CC)c1ccc(N)cc1

化学属性

Mol. FormulaC10H16N2
Mol. Weight164
Density0.988
Refractive indexn20/D 1.571(lit.)
Boiling Point268
Melting Point23
Flash Point139°C(lit.)
Solubility<0.1 G/100 ML AT 19 ºC
Appearance 浅黄色液体。熔点23℃,沸点260-262℃,115-116℃(0.67kPa)。相对密度0.988。 能与醇、醚混合,不溶于水。遇光或暴露在空气中变色。
Stability对光和空气敏感

别名和识别编码

Chemical NameN,N-Diethyl-p-Phenylenediamine
CAS Number93-05-0
Alfabeta NameDIETHYLBENZENEDIAMINE NN1114-----,,
MDL NumberMFCD00007861
EC Number202-214-1
Beilstein Registry Number879361
Synonym 4-Amino-N,N-diethylaniline 4-Aminodiethylaniline 4-Diethylaminoaniline 4-氨基-N,N-二乙苯胺 AKOS 91152 N,N'-Diethyl-p-fenylendiamin N,N-DIETHYL-1,4-BENZENEDIAMINE N,N-DIETHYL-1,4-PHENYLENEDIAMINE N,N-Diethyl-1,4-benzenediamine P-AMINODIETHYLANILINE diethylaminoaniline n,n-diethyl-1,4-phenylenediamine.html p-(Diethylamino)aniline 二乙基-N,N-对苯二胺 二乙基对苯二胺 对氨基-N,N-二乙基苯胺
PubChem Substance ID87567181
Chemical Name TranslationN,N-二乙基对苯二胺
Reaxys-RN879361
Wiswesser Line NotationZR DN2&2
LabNetwork Molecule IDLN00153282
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Polyamines

安全信息

Warnings IRRITANT
Signal word Danger
GHS Symbol
WGK Germany1
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P310+P330
  • P301+P330+P331
  • P301+P330+P331+P310
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSSS9275000
Hazard Codes 8 T
UN Number 2922 2923
Storage condition <;0 <0°C Freezer
Packing GroupIII
Hazard Class8/6.1
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIDHAN Journal of Industrial Hygiene.  (Cambridge, MA)  V.1-17, 1919-35. For
   publisher information, see AEHLAU.  Volume(issue)/page/year: 4,386,1923

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - food intake (animal)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS 0546494

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
REFERENCE :
   JIDHAN Journal of Industrial Hygiene.  (Cambridge, MA)  V.1-17, 1919-35. For
   publisher information, see AEHLAU.  Volume(issue)/page/year: 4,386,1923

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - coma
REFERENCE :
   JIDHAN Journal of Industrial Hygiene.  (Cambridge, MA)  V.1-17, 1919-35. For
   publisher information, see AEHLAU.  Volume(issue)/page/

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 666 ug/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 2500 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 241,175,1990

其他信息

  • 图谱信息:N,N-二乙基对苯二胺(93-05-0)红外图谱(IR1) N,N-二乙基对苯二胺(93-05-0)核磁图( 13 CNMR) N,N-二乙基对苯二胺(93-05-0)质谱(MS) N,N-二乙基对苯二胺(93-05-0)核磁图( 1 HNMR)
  • Sigma Aldrich:93-05-0(sigmaaldrich)
  • MOL 文件:93-05-0.mol
  • 用途一:用作医药中间体
  • N,N-二乙基对苯二胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 A26151301 N,N-二乙基-1,4-苯二胺,97% 25g 640元 2011/08/23 k0766001 N.N-二乙基对苯二胺 100ml 1225元 2011/08/23 M82040003 N,N-二乙基对苯二胺 25ml 346元
  • TCI Shanghai:N,N-二乙基对苯二胺 N,N-Diethyl-1,4-phenylenediamine,>;98.0%(T)(93-05-0)
  • 下游产品:对氨基二乙基苯胺硫酸盐
  • 上游原料:氯化钠 --> 铁粉 --> Α-球蛋白 --> 硝基物 --> N,N-二乙基-4-硝基苯胺
  • Acros Organics:N,N-二乙基对苯二胺 N,N-Diethyl-p-phenylenediamine, 98%(93-05-0)
  • 方法一:以N,N-二乙基苯胺为原料,经亚硝化、还原、中和而得:工艺过程如下:(1)亚硝化 在釜中加入150kg水,35kg N,N-二乙基苯胺和72kg盐酸,冷至0℃。在0-5℃,加入50%亚硝酸钠溶液(以100%18.5kg配成)。加毕,搅拌半小时,加入6kg食盐。搅拌2h。过滤得对亚硝基-N,N-二乙基苯胺。(2)还原、中和 在釜中加入150kg水及11kg盐酸。搅拌,加入41kg铁粉,降温至15℃,在20-25℃加亚硝基物。加毕,补加铁粉5kg,在20-25℃搅拌3h。加入碳酸钠7kg,搅拌15min,过滤。滤饼以热水洗涤。滤液和洗液中加入50kg液碱(30%),15kg食盐,静置分层。上层物料蒸馏釜,于120-150℃及真空度为8kPa减压蒸馏收集馏分,得对氨基-N,N-二乙基苯胺。
  • MSDS 信息:N,N-Diethyl-1,4-phenylenediamine(93-05-0).msds
  • 海关编码:29215190
  • 用途二:染料中间体。作彩色相显影剂。

系列性分类


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