Artemisinin 青蒿素

CAS 63968-64-9 MFCD00081057

化学结构图

63968-64-9
SMILES: C[C@@]12CC[C@H]3[C@H](C)CC[C@H]4[C@@H](C)C(=O)O[C@H](O1)[C@]43OO2

化学属性

Mol. FormulaC15
Mol. Weight282
Melting Point156-157

别名和识别编码

Chemical NameArtemisinin
CAS Number63968-64-9
Synonym Arteannuin Artemisia annua L., extract Qinghaosu Qinghosu Artemisinin Artemisine Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one Huanghuahaosu Arteannuin Qinghaosu Qing Hau Sau
MDL NumberMFCD00081057
PubChem Substance ID87560451
Reaxys-RN4194670
Chemical Name Translation青蒿素
Merck Number817
Beilstein Registry Number4194670
LabNetwork Molecule IDLN00836025
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Antiviral, Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM), Spectrum of Activity, 抗生素, 生化试剂, 细胞生物学, 营养研究
  • {SNA} Antibiotics, Antiviral, Nutrition Research, Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM), Spectrum of Activity
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.

相关文献及参考

  • Klayman, D.L., et al.: Science, 228, 1049 (1985),
  • Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000),
  • Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),

安全信息

WGK Germany2
RTECSKD4170000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Safety Statements
Precautionary statements 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4228 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   JTCMEC Journal of Traditional Chinese Medicine (English Edition). (All-China
   Assoc. of Traditional Chinese Medicine, Academy of Traditional Chinese
   Medicine)  V.1-    1981-  Volume(issue)/page/year: 2,31,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year:
   92,811,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1558 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year:
   92,811,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5576 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   JTCMEC Journal of Tradit

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Spectrum of Activity - Antibiotics
  4. Antiviral - Spectrum of Activity

相关产品推荐