Naratriptan Hydrochloride 盐酸那拉曲坦

CAS 143388-64-1 MFCD08141821

化学结构图

143388-64-1
SMILES: CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1.Cl

化学属性

Mol. FormulaC17H26ClN3O2S
Mol. Weight372

别名和识别编码

Chemical NameNaratriptan Hydrochloride
CAS Number143388-64-1
Synonym 1H-indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, monohydrochloride Amerge Amerge GR-85548A N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride Colatan GR 85548A GR-85548A N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide Hydrochloride N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide N-methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide monohydrochloride Naramig Naratriptan hydrochloride naratriptan naratriptan hydrochloride
MDL NumberMFCD08141821
PubChem Substance ID60875
Chemical Name Translation盐酸那拉曲坦
InChIInChI=1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H
LabNetwork Molecule IDLN01300572
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分类

  • Pharmaceuticals
  • {SNA} Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, N, Neuroscience,

产品应用

  • It is a triptan drug and is used for the treatment of migraine headaches.

相关文献及参考

  • Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997),
  • Havanka, H., et al.: Clin. Ther., 22, 970 (2000),
  • [1]. Connor HE, et al. Naratriptan: biological profile in animal models relevant to migraine. Cephalalgia. 1997 May;17(3):145-52.

安全信息

GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P337+P313
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Hazard Codes Xi
Risk Statements
  • R36 Irritating to eyes 刺激眼睛

系列性分类


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