(13)Cytochalasa-13,17,21-triene-1,20,23-trione,6,7-epoxy-19-hydroxy-10-(1H-indol-3-yl)-16,18-dimethyl-, (7S,13E,16S,17E,19R,21E)-

CAS 50335-03-0 MFCD08273781

化学结构图

50335-03-0
SMILES: C[C@]12O[C@H]1[C@@H]1C=CCC(C)C=C(C)[C@@H](O)C(=O)C=CC(=O)[C@]31[C@H]([C@H](CC1=CNC4C=CC=CC=41)NC3=O)[C@@H]2C |c:11,31,33,t:6,18,27|

化学属性

Mol. FormulaC32H36N2O5
Mol. Weight528.70

别名和识别编码

Chemical Name(13)Cytochalasa-13,17,21-triene-1,20,23-trione,6,7-epoxy-19-hydroxy-10-(1H-indol-3-yl)-16,18-dimethyl-, (7S,13E,16S,17E,19R,21E)-
Synonym Chaetoglobosin A
Beilstein Registry Number1097707
CAS Number50335-03-0
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

安全信息

RTECSHA5305000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJEMAG Japanese Journal of Experimental Medicine.  (Kinokuniya Book-Stores
   of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581
   Webster St., San Francisco, CA 94115) V.7-    1928- Volume(issue)/page/year:
   48,105,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6500 ug/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
   JJEMAG Japanese Journal of Experimental Medicine.  (Kinokuniya Book-Stores
   of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581
   Webster St., San Francisco, CA 94115) V.7-    1928- Volume(issue)/page/year:
   48,105,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJEMAG Japanese Journal of Experimental Medicine.  (Kinokuniya Book-Stores
   of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581
   Webster St., San Francisco, CA 94115) V.7-    1928- Volume(issue)/page/year:
   48,105,1978

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Gastrointestinal - other changes
   Liver - other changes
REFERENCE :
   JJEMAG Ja

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 700 ug/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   MAIKD3 Maikotokishin (Tokyo).  Mycotoxin.  (Maikotokishin Kenkyukai, c/o
   Tokyo Rika Daigaku Yakugakubu, 12 Funagawara-machi, Ichigaya, Shinjuku-ku,
   Tokyo 162, Japan)  No.1-    1975-  Volume(issue)/page/year: (10),17,1980

系列性分类

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