4-Morpholinecarboxamide, N,N'-ethylenebis(N-butyl-

CAS 119-48-2 MFCD00864195

化学结构图

119-48-2
SMILES: CCCCN(CCN(CCCC)C(=O)N1CCOCC1)C(=O)N1CCOCC1

化学属性

Mol. FormulaC20H38N4O4
Mol. Weight398.62

别名和识别编码

Chemical Name4-Morpholinecarboxamide, N,N'-ethylenebis(N-butyl-
Wiswesser Line NotationT6N DOTJ AVN4&2N4&V- AT6N DOTJ
Synonym Dimorpholamine Prontodin 1064 TH Amipan T N,N'-Ethylenebis(N-butyl-4-morpholinecarboxamide) N,N'-1,2-Ethanediylbis(N-butyl-4-morpholinecarboxamide) N,N'-Dibutyl-N,N'-dicarboxymorpholide-ethylenediamine N,N'-Dibutyl-N,N'-dicarboxyethylene diaminemorpholide Atmurin N,N'-Di-n-butylethylenediamine-N,N'-dicarboxybismorpholide Theraleptique Theraptique
CAS Number119-48-2
Beilstein Registry Number0052277
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安全信息

RTECSQD9800000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 163,133,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 122 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,347,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 270 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,347,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 190 mg/k

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,347

系列性分类

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