Epanolol
CAS 86880-51-5 MFCD00864564
化学结构图
SMILES: N#CC1C=CC=CC=1OCC(O)CNCCNC(=O)CC1=CC=C(O)C=C1
化学属性
| Mol. Formula | C20H23N3O4 |
|---|---|
| Mol. Weight | 369.41 |
别名和识别编码
| Chemical Name | Epanolol |
|---|---|
| CAS Number | 86880-51-5 |
| Synonym | N-[2-[[3-(2-Cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-hydroxybenzeneacetamide ICI 141292 Visacor |
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Epanolol is a adrenergic ?-antagonist. Epanolol is used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
相关文献及参考
- Andrews, C., et al.: Pharm. Res., 17, 639 (2000),
- Chen, M., et al.: Pharm. Res., 18, 1645 (2001),
- Votano, J., et al.: J. Med. Chem., 49, 7169 (2006),
- [1]. Hosie J, et al. Pharmacokinetics of epanolol after acute and chronic oral dosing in elderly patients with stable angina pectoris. Br J Clin Pharmacol. 1990 Mar;29(3):333-7.
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