2-Furancarboxylic acid, 1-(2,2-dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester 1-(二氯乙酰基)-6-(2-呋喃甲酰氧基)-1,2,3,4-四氢喹啉

CAS 62265-68-3 MFCD00864662

化学结构图

62265-68-3
SMILES: O=C(C(Cl)Cl)N1CCCC2C=C(C=CC1=2)OC(=O)C1=CC=CO1

化学属性

Mol. FormulaC16H13Cl2NO4
Mol. Weight354.20

别名和识别编码

Chemical Name2-Furancarboxylic acid, 1-(2,2-dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
CAS Number62265-68-3
Synonym Quinfamide 2-Furancarboxylic Acid 1-(2,2-Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl Ester Amenide 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline Win 40014 Amenox 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydro-6-quinoline
Beilstein Registry Number1554485
Chemical Name Translation1-(二氯乙酰基)-6-(2-呋喃甲酰氧基)-1,2,3,4-四氢喹啉
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • An antiamebic agent, used to treat tropical parasitic infections

相关文献及参考

  • Slighter, R., et al.: Parasitol., 81, 157 (1980),
  • Parthasarathy, P., et al.: Eur. J. Med. Chem., 28, 195 (1993),
  • Padilla, N., et al.: Clin. Drug Invest., 20, 89 (2000),

安全信息

RTECSLU0215000 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,599,1979

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,599,1979

系列性分类

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