TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 39 mg/kg/78W-I TOXIC EFFECTS : Peripheral Nerve and Sensation - associated connective tissue Blood - leukopenia Skin and Appendages - dermatitis, other (after systemic exposure) REFERENCE : ARHEAW Arthritis and Rheumatism. (Arthritis Foundation, 1314 Spring St., NW, Atlanta, GA 30309) V.1- 1958- Volume(issue)/page/year: 31,145,1988