2-Propen-1-aminium,N-(2-amino-2-oxoethyl)-3-(7-(((5-amino-1,2,4-thiadiazol-3-yl)((fluoromethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4. 2.0)oct-2-en-3-yl)-N-ethyl-N-methyl-, inner salt,(6R-(3(E),6-alpha,7-beta(Z)))-
CAS 116853-25-9 MFCD00864845
化学结构图
SMILES: CC[N+](C)(CC(N)=O)C/C=C/C1CS[C@@H]2[C@H](NC(=O)/C(=N\OCF)/C3N=C(N)SN=3)C(=O)N2C=1C([O-])=O
化学属性
| Mol. Formula | C20H25FN8O6S2 |
|---|---|
| Mol. Weight | 556.65 |
别名和识别编码
| Chemical Name | 2-Propen-1-aminium,N-(2-amino-2-oxoethyl)-3-(7-(((5-amino-1,2,4-thiadiazol-3-yl)((fluoromethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4. 2.0)oct-2-en-3-yl)-N-ethyl-N-methyl-, inner salt,(6R-(3(E),6-alpha,7-beta(Z)))- |
|---|---|
| Synonym | Cefluprenam E 1077 Antibiotic E 1077 |
| CAS Number | 116853-25-9 |
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安全信息
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >4 gm/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 25(Suppl 6),S1245,1997
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >4 gm/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 25(Suppl 6),S1245,1997
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