4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylicacid, 3-(((aminocarbonyl)oxy)methyl)-6-(1-hydroxyethyl)-7-oxo-, (5R-(5alpha,6alpha(R*)))-

CAS 84845-57-8 MFCD00864941

化学结构图

84845-57-8
SMILES: C[C@@H](O)[C@@H]1[C@H]2SC(COC(N)=O)=C(C(O)=O)N2C1=O

化学属性

Mol. FormulaC10H12N2O6S
Mol. Weight288.30

别名和识别编码

Chemical Name4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylicacid, 3-(((aminocarbonyl)oxy)methyl)-6-(1-hydroxyethyl)-7-oxo-, (5R-(5alpha,6alpha(R*)))-
Synonym Ritipenem
CAS Number84845-57-8
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安全信息

RTECSXI0191750 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Nutritional and Gross Metabolic - changes in potassium
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 29,3475,1995

系列性分类

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