1-((2-fluorophenyl)(4-fluorophenyl)(phenyl)methyl)-1H-imidazole 1-[(2-氟苯基)(4-氟苯基)(苯基)甲基]咪唑
CAS 119006-77-8 MFCD00865591
化学结构图
SMILES: FC1C=CC(=CC=1)C(C1=CC=CC=C1F)(C1C=CC=CC=1)N1C=NC=C1
化学属性
| Mol. Formula | C22H16F2N2 |
|---|---|
| Mol. Weight | 346.40 |
别名和识别编码
| Chemical Name | 1-((2-fluorophenyl)(4-fluorophenyl)(phenyl)methyl)-1H-imidazole |
|---|---|
| Chemical Name Translation | 1-[(2-氟苯基)(4-氟苯基)(苯基)甲基]咪唑 |
| Synonym | Flutrimazol Flutrimazole 1-(o-Fluoro-alpha-(p-fluorophenyl)-alpha-phenylbenzyl)imidazole 1-((2-Fluorophenyl)(4-fluorophenyl)phenylmethyl)-1H-imidazole UR-4056 |
| Beilstein Registry Number | 5383184 |
| CAS Number | 119006-77-8 |
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安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 808 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 42,841,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1079 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - respiratory depression REFERENCE : ARZ
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