7-Benzofuranacetic acid, alpha-methyl-3-phenyl-,(+-)-

CAS 67700-30-5 MFCD00866055

化学结构图

67700-30-5
SMILES: CC(C(O)=O)C1=CC=CC2=C1OC=C2C1C=CC=CC=1

化学属性

Mol. FormulaC17H14O3
Mol. Weight266.31

别名和识别编码

Chemical Name7-Benzofuranacetic acid, alpha-methyl-3-phenyl-,(+-)-
Wiswesser Line NotationT56 BOJ DR& IY1&VQ
Synonym Furaprofen Enprofen (+-)-alpha-Methyl-3-phenyl-7-benzofuranacetic acid R-803
CAS Number67700-30-5
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安全信息

RTECSDF6424000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 214,240,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   JCPCBR Journal of Clinical Pharmacology.  (Hall Assoc., PO Box 482,
   Stamford, CT 06904) V.13-    1973-  Volume(issue)/page/year: 16,473,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 214,240,1975

系列性分类

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