Amtolmetin guacil 呱氨托美丁

CAS 87344-06-7 MFCD00866153

化学结构图

87344-06-7
SMILES: CC1C=CC(=CC=1)C(=O)C1=CC=C(CC(=O)NCC(=O)OC2=CC=CC=C2OC)N1C

化学属性

Mol. FormulaC24H24N2O5
Mol. Weight420

别名和识别编码

Chemical NameAmtolmetin guacil
CAS Number87344-06-7
Alfabeta NameMETHOXYPHENYLMETHYLMETHYLBENZOYLPYRROLYLACETAMIDOACETATE H22215412((()))-----------
MDL NumberMFCD00866153
Synonym Amtolmetin guacil Amtolmetin Guacyl MED 15 2-Methoxyphenyl 1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate Amtolmethin Guacil N-((1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetyl)glycine N-[2-[1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]glycine 2-Methoxyphenyl Ester
Chemical Name Translation呱氨托美丁
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Analgesic; anti-inflammatory used in the treatment of rheumatoid arthritis,

相关文献及参考

  • Montrone, F., et al.: J. Int. Med. Res., 28, 91 (2000),

安全信息

Warnings IRRITANT
RTECSMC0598400 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2115417

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2115417

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2115417

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BAXXDU British UK Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2115417

系列性分类

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