7-Benzofurancarboxamide,2,3-dihydro-5-chloro-2,2-dimethyl-N-(8-methyl-8-azabicyclo(3.2.1)oct-3-yl) -, endo-, (Z)-2-butenedioate(1:1)

CAS 123482-23-5 MFCD00866225

化学结构图

123482-23-5
SMILES: CN1[C@@H]2C[C@H](C[C@H]1CC2)NC(=O)C1=CC(Cl)=CC2CC(C)(C)OC=21.OC(=O)/C=C\C(O)=O |&1:2,4,6|

化学属性

Mol. FormulaC19H25ClN2O2.C4H4O4
Mol. Weight464.99

别名和识别编码

Chemical Name7-Benzofurancarboxamide,2,3-dihydro-5-chloro-2,2-dimethyl-N-(8-methyl-8-azabicyclo(3.2.1)oct-3-yl) -, endo-, (Z)-2-butenedioate(1:1)
Synonym Zatosetron maleate LY 277359 maleate
CAS Number123482-23-5
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相关文献及参考

  • [2]. Rasmussen K, et al. The 5-HT3 receptor antagonist zatosetron decreases the number of spontaneously active A10 dopamine neurons. Eur J Pharmacol. 1991 Nov 19; 205 (1):113-6.
  • [1]. Robertson DW, et al. Zatosetron, a potent, selective, and long-acting 5HT3 receptor antagonist: synthesis and structure-activity relationships. J Med Chem. 1992 Jan 24;35(2):310-9.
  • [1]. Robertson DW, et al. Zatosetron, a potent, selective, and long-acting 5HT3 receptor antagonist: synthesis and structure-activity relationships. J Med Chem. 1992 Jan 24;35(2):310-9.
  • [2]. Rasmussen K, et al. The 5-HT3 receptor antagonist zatosetron decreases the number of spontaneously active A10 dopamine neurons. Eur J Pharmacol. 1991 Nov 19; 205 (1):113-6.

安全信息

RTECSDF6473550

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. 5-HT Receptor  (5-羟色胺受体)

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