1-Butanone,4-(4-(4-fluorobenzoyl)-1-piperidinyl)-1-(4-fluorophenyl)-
CAS 24678-13-5 MFCD00866667
化学结构图
SMILES: O=C(CCCN1CCC(CC1)C(=O)C1C=CC(F)=CC=1)C1=CC=C(F)C=C1
化学属性
| Mol. Formula | C22H23F2NO2 |
|---|---|
| Mol. Weight | 371.46 |
别名和识别编码
| Chemical Name | 1-Butanone,4-(4-(4-fluorobenzoyl)-1-piperidinyl)-1-(4-fluorophenyl)- |
|---|---|
| CAS Number | 24678-13-5 |
| Synonym | Lenperone Lenperonum (Latin) 4-(4-(4-Fluorobenzoyl)-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone Lenperona 4'-Fluoro-4-(4-(p-fluorobenzoyl)piperidino)butyrophenone 4-[4-(4-Fluorobenzoyl)-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone AHR-2277 |
| Beilstein Registry Number | 1554429 |
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分类
- Aromatics
- Heterocycles
- Neurochemicals
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Lenperone is a neuroleptic butyrophenone. Lenperone is an effective atypical antipsychotic drug used in the treatment of schizophrenia.
相关文献及参考
- Zbinden, G. et al.: Arzneim.-Forsch., 30, 1709 (1980); Seeman, P. et al.: Nature, 261, 717 (1976);
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 90100 ug/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS REFERENCE : DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 4,1,1978
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