Phenothiazine,2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)-

CAS 14759-04-7 MFCD00866679

化学结构图

14759-04-7
SMILES: CN1CCCCC1CCN1C2C=C(C=CC=2SC2C=CC=CC1=2)OC

化学属性

Mol. FormulaC21H26N2OS
Mol. Weight354.55

别名和识别编码

Chemical NamePhenothiazine,2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)-
Synonym Oxyridazine 2-Methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazine KS-33 3-Methoxy-10-(2'-(N-methylpiperidyl-2')-ethyl)phenothiazine 10H-Phenothiazine, 2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)-
Wiswesser Line NotationT C666 BN ISJ EO1 B2- BT6NTJ A1
CAS Number14759-04-7
Beilstein Registry Number6118065
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安全信息

RTECSSP0875000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIGZAY Niigata Igakkai Zasshi.  Niigata Medical Journal.  (Niigata Igakkai,
   1, Asahi-machi, Niigata 951, Japan)  V.60-    1946- Volume(issue)/page/year:
   82,607,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   65(2),104S,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 516 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   65(2),104S,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :

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