1-(2-(4-(5-Chloro-1-(4-Fluorophenyl)-1H-Indol-3-yl)Piperidin-1-yl)Ethyl)Imidazolidin-2-One 1-(2-(4-(5-氯-1-(4-氟苯基)-1H-吲哚-3-基)哌啶-1-基)乙基)咪唑烷-2-酮

CAS 106516-24-9 MFCD00867749

化学结构图

106516-24-9
SMILES: O=C1NCCN1CCN1CCC(CC1)C1=CN(C2C=CC(Cl)=CC=21)C1C=CC(F)=CC=1

化学属性

Mol. FormulaC24H26ClFN4O
Mol. Weight440.95

别名和识别编码

Chemical Name1-(2-(4-(5-Chloro-1-(4-Fluorophenyl)-1H-Indol-3-yl)Piperidin-1-yl)Ethyl)Imidazolidin-2-One
CAS Number106516-24-9
Synonym 1-[2-[4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-1h-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinone Serdolect Sertindole Zerdol
MDL NumberMFCD00867749
Chemical Name Translation1-(2-(4-(5-氯-1-(4-氟苯基)-1H-吲哚-3-基)哌啶-1-基)乙基)咪唑烷-2-酮
PubChem Substance ID253660923
Reaxys-RN5364890
Merck Number8466
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分类

  • {SNA} Abbott, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, S, Serotonergics, Serotonergics - Antagonists
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Aromatics
  • {SNA} Abbott, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Diversification Ready Pharma-Developed Compounds, GPCR Modulators,

产品应用

  • Antipsychotic used in the treatment of schizophrenia.

相关文献及参考

  • Nourian, Z., et al.: Eur. J. Pharmacol., 596, 32 (2008),

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
WGK Germany3
Signal word Warning
RTECSNJ0621100
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 0-10°C

系列性分类


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