Acetonitrile, ((alpha-methylphenethyl)amino)phenyl-

CAS 17590-01-1 MFCD00867905

化学结构图

17590-01-1
SMILES: CC(CC1C=CC=CC=1)NC(C#N)C1C=CC=CC=1

化学属性

Mol. FormulaC17H18N2
Mol. Weight250.37

别名和识别编码

Chemical NameAcetonitrile, ((alpha-methylphenethyl)amino)phenyl-
CAS Number17590-01-1
Synonym dl-Amphetaminil Aponeuron alpha-Phenyl-alpha-N-(1-phenylisopropyl)aminoacetonitrile AN 1 (pharmaceutical) ######## Amphetaminil alpha-Phenyl-alpha-(1-methyl-2-phenyl)ethylaminoacetonitrile N-(alpha-Methylphenethyl)-2-phenylglycinonitrile alpha-Phenyl-alpha(beta-phenylisopropylamino)acetonitrile Benzeneacetonitrile, alpha-((1-methyl-2-phenylethyl)amino)-
Wiswesser Line NotationNCYR&MY1&1R
Beilstein Registry Number2056148
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Psychotropic.

相关文献及参考

  • Beyrich, et al.: Pharmazie, 27, 28 (1972),
  • Remberg, et al.: Arch. Toxicol., 29, 153 (1972),

安全信息

RTECSAM1050000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 95100 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP elevation not characterized in autonomic section
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 24,823,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 491 mg/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP elevation not characterized in autonomic section
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 24,823,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 37600 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP elevation not characterized in autonomic section
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 24,823,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

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系列性分类


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