N1,N3-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-5-(2-Methoxyacetamido)-N1-Methylisophthalamide N1,N3-双(2,3-二羟丙基)-2,4,6-三碘-5-(2-甲氧基乙酰胺)-N1-甲基间苯二甲酰胺

CAS 73334-07-3 MFCD00867924

化学结构图

73334-07-3
SMILES: COCC(=O)NC1C(I)=C(C(I)=C(C=1I)C(=O)N(C)CC(O)CO)C(=O)NCC(O)CO

化学属性

Mol. FormulaC18H24I3N3O8
Mol. Weight791

别名和识别编码

Chemical NameN1,N3-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-5-(2-Methoxyacetamido)-N1-Methylisophthalamide
CAS Number73334-07-3
Synonym N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl- Ultravist Iopromide SHL 414C
Chemical Name TranslationN1,N3-双(2,3-二羟丙基)-2,4,6-三碘-5-(2-甲氧基乙酰胺)-N1-甲基间苯二甲酰胺
Beilstein Registry Number7085608
MDL NumberMFCD00867924
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分类

  • Amines
  • Aromatics
  • Diagnostic
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).

相关文献及参考

  • Muetzel, W., et al.: Am.J. Neuroradiol., 4, 350 (1983),
  • Dawson, P., et al.: Acta Radiol. Diagn., 25, 253 (1984),

安全信息

RTECSCZ2230000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 21403 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARASA5 Acta Radiologica, Supplementum.  (Acta Radiologica, POB 7449, S-10391
   Stockholm, Sweden) No.1-    1921-  Volume(issue)/page/year: 370,41,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >21 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1275,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AAJNDL AJNR, American Journal of Neuroradiology.  (Williams & Wilkins Co.,
   428 E. Preston St., Baltimore, MD 21202)  V.1-    1980-
   Volume(issue)/page/year: 4,350,1983

系列性分类

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