Ketone, 10-(3-(dimethylamino)propyl)phenothiazin-2-ylmethyl 乙酰普马嗪(乙酰丙嗪)

CAS 61-00-7 MFCD00867988

化学结构图

61-00-7
SMILES:

化学属性

Mol. FormulaC19H22N2OS
Mol. Weight326.49

别名和识别编码

Chemical NameKetone, 10-(3-(dimethylamino)propyl)phenothiazin-2-ylmethyl
Wiswesser Line NotationT C666 BN ISJ B3N1&1 EV1
Synonym SV-1522 Acetopromazine AY-57,062 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)ethanone 1522 CB Acepromazine 10-(3-Dimethylaminopropyl)phenothiazine-3-ethylone Plivafen Anergan Acetylpromazine Plegicil Atsetozin Vetranquil 10-(3-Dimethylaminopropyl)phenothiazin-3-yl methyl ketone Acepromazina WY-1172 Notensil Azepromazine Ethanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)- Promazine, acetyl- 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine
CAS Number61-00-7
Chemical Name Translation乙酰普马嗪(乙酰丙嗪)
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安全信息

RTECSOB2275000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 113,53,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 59 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,1,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RMNIBN Revista Medico-Chirurgicala.  Medical-Surgical Journal.  (Societatea
   de Medici si Naturalisti, 16 Bulevardul Independentei, Iasi, Romania) V.35- 
     1924-  Volume(issue)/page/y

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 113,53,1957

系列性分类

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