Ergoline-8-carboxamide,N-cyclohexyl-6-methyl-1-(1-methylethyl)-, (8-beta)-

CAS 121588-75-8 MFCD00868058

化学结构图

121588-75-8
SMILES: CN1C[C@@H](C[C@H]2[C@H]1CC1=CN(C(C)C)C3C=CC=C2C1=3)C(=O)NC1CCCCC1

化学属性

Mol. FormulaC25H35N3O
Mol. Weight393.63

别名和识别编码

Chemical NameErgoline-8-carboxamide,N-cyclohexyl-6-methyl-1-(1-methylethyl)-, (8-beta)-
Synonym Amesergide LY237733
CAS Number121588-75-8
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安全信息

RTECSKE2850000 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 195 mg/kg
SEX/DURATION            : female 6-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   27,247,1995

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 360 mg/kg
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   27,247,1995

系列性分类

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