4H-3,1-Benzoxazine,6-chloro-2-ethylamino-4-methyl-4-phenyl-

CAS 21715-46-8 MFCD00868190

化学结构图

21715-46-8
SMILES: CCNC1=NC2=CC=C(Cl)C=C2C(C)(O1)C1C=CC=CC=1

化学属性

Mol. FormulaC17H17ClN2O
Mol. Weight300.81

别名和识别编码

Chemical Name4H-3,1-Benzoxazine,6-chloro-2-ethylamino-4-methyl-4-phenyl-
Wiswesser Line NotationT66 BN DO EHJ CM2 E1 ER& HG
Synonym HOE 36801 4H-3,1-Benzoxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl- 6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine Etifoxine 2-Aethylamino-6-chlor-4-methyl-4-phenyl-4H-3,1-benzoxazin Etifoxin
Beilstein Registry Number0548223
CAS Number21715-46-8
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安全信息

RTECSDM3028000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 27,325,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 292 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 27,325,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1388 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal d

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 27,325,1

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 27,325,1972

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