2-Oxazolin-4-one, 2-(cyclopropylamino)-5-phenyl-

CAS 14461-91-7 MFCD00869038

化学结构图

14461-91-7
SMILES: O=C1N=C(NC2CC2)OC1C1=CC=CC=C1

化学属性

Mol. FormulaC12H12N2O2
Mol. Weight216.26

别名和识别编码

Chemical Name2-Oxazolin-4-one, 2-(cyclopropylamino)-5-phenyl-
CAS Number14461-91-7
Synonym LD 3695 2-(Cyclopropylamino)-5-phenyl-4(5H)-oxazolone 2-(Cyclopropylamino)-5-phenyl-2-oxazolin-4-one 2-(Cyclopropylamino)-5-phenyl- Phenyl-5 cyclopropylamino-2 oxazolinone-4
Beilstein Registry Number3959190
Chemical Name Translation
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分类

  • Amines
  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Pemoline (P220100) and Cyclopropylpemoline seem to be basically central stimulants with a mechanism of action similar to that of d-Amphetamine.

相关文献及参考

  • Politi, L., et al.: Clin. Chim. Acta., 386, 46 (2007),
  • Thevis, M., et al.: Anal. Bioanal. Chem., 388, 1351 (2007),
  • Kuuranne, T., et al.: Drug Metab. Dispos., 36, 571 (2008),

安全信息

RTECSRQ5762000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHDDAT Comptes Rendus des Seances de l'Academie des Sciences, Serie D:
   Sciences Naturelles.  (Paris, France)  V.262-291, 1966-80.  For publisher
   information, see CRASEV.  Volume(issue)/page/year: 262,213,1966

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Cyclopropy 环丙基化合物

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