4-Isothiazolecarboxamide,5-(benzoylamino)-N-(p-chlorophenyl)-3-methyl-

CAS 51287-57-1 MFCD00869136

化学结构图

51287-57-1
SMILES: CC1=NSC(NC(=O)C2C=CC=CC=2)=C1C(=O)NC1C=CC(Cl)=CC=1

化学属性

Mol. FormulaC18H14ClN3O2S
Mol. Weight371.86

别名和识别编码

Chemical Name4-Isothiazolecarboxamide,5-(benzoylamino)-N-(p-chlorophenyl)-3-methyl-
Synonym 5-(Benzoylamino)-N-(p-chlorophenyl)-3-methyl-4-isothiazolecarboxamide p-Chlorophenylamide of 3-methyl-5-benzoylaminoizothiazole-4-carboxylic
CAS Number51287-57-1
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安全信息

RTECSNX8155650 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   28,393,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   28,393,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   28,393,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 219 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volu

系列性分类

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