Acetohydroxamic acid, N-(4-ethoxyphenyl)-

CAS 19315-64-1 MFCD00869380

化学结构图

19315-64-1
SMILES: CC(=O)N(O)C1C=CC(=CC=1)OCC

化学属性

Mol. FormulaC10H13NO3
Mol. Weight195.24

别名和识别编码

Chemical NameAcetohydroxamic acid, N-(4-ethoxyphenyl)-
Wiswesser Line NotationQMV1R DO2
Synonym Acetamide, N-(4-ethoxyphenyl)-N-hydroxy- N-(4-Ethoxyphenyl)acetohydroxamic acid N-Hydroxyphenacetin N-Hydroxy-p-acetophenetidide p-Acetophenetidide, N-hydroxy- N-(p-Ethoxyphenyl)acetohydroxamic acid Acetohydroxamic acid, N-(p-ethoxyphenyl)- N-(4-Ethoxyphenyl)-N-hydroxyacetamide
Beilstein Registry Number2104196
CAS Number19315-64-1
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 gm/kg/73W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   PTLGAX Pathology.  (Royal College of Pathologists of Australia, 82 Windmill
   St., Sydney, NSW, Australia)  V.1-    1969-  Volume(issue)/page/year:
   8,1,1976

RTECSAK8380000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 6,76,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 702 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   56,96,1984

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,367,1978

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 100 ug/L
REFERENCE :
   NCIMAV National Cancer Institute, Monograph.  (U.S. Government Printing
   Office, Supt. of Documents, Washington, DC 20402)  No.1-    1959-
   Volume(issue)/page/year: 58,21,1981

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - rat Kidney
DOSE/DURATION           : 5 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 189,299,1987

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