Carbamic acid, (3-(pentyloxy)phenyl)-,2-(1-pyrrolidinyl)cyclohexyl ester, trans-(+-)-

CAS 104485-01-0 MFCD00869494

化学结构图

104485-01-0
SMILES: CCCCCOC1C=CC=C(C=1)NC(=O)O[C@@H]1CCCC[C@H]1N1CCCC1 |&1:16,21|

化学属性

Mol. FormulaC22H34N2O3
Mol. Weight374.58

别名和识别编码

Chemical NameCarbamic acid, (3-(pentyloxy)phenyl)-,2-(1-pyrrolidinyl)cyclohexyl ester, trans-(+-)-
Synonym Pentacaine Pentakain trans-(+-)-2-(1-Pyrrolidinyl)cyclohexyl (3-(pentyloxy)phenyl)carbamate
CAS Number104485-01-0
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安全信息

RTECSFD0406500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAOBAS Farmaceuticky Obzor.  Pharmaceutical Review.  (PNS - Ustredna
   Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
   Czechoslovakia)  V.30-    1961-  Volume(issue)/page/year: 45,355,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAOBAS Farmaceuticky Obzor.  Pharmaceutical Review.  (PNS - Ustredna
   Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
   Czechoslovakia)  V.30-    1961-  Volume(issue)/page/ye

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1030 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAOBAS Farmaceuticky Obzor.  Pharmaceutical Review.  (PNS - Ustredna
   Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
   Czechoslovakia)  V.30-    1961-  Volume(issue)/page/year: 45,355,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 283 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAOBAS Farmaceuticky Obzor.  Pharmaceutical Review.  (PNS - Ustredna
   Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava,
   Czechoslovakia)  V.30-    1961-  Volume(issue)/

系列性分类

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