(R)-Carvedilol (R)-卡维地洛
CAS 95093-99-5 MFCD00869663
化学结构图
SMILES: COC1=CC=CC=C1OCCNC[C@@H](O)COC1=CC=CC2NC3C=CC=CC=3C=21
化学属性
| Mol. Formula | C24H26N2O4 |
|---|---|
| Mol. Weight | 406.47 |
别名和识别编码
| Chemical Name | (R)-Carvedilol |
|---|---|
| CAS Number | 95093-99-5 |
| Synonym | (+)-1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol (+)-Carvedilol (R)-Carvedilol |
| Chemical Name Translation | (R)-卡维地洛 |
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分类
- Aromatics
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- The optically active isomer of Carvedilol (C184625), a nonselective ?-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.
相关文献及参考
- Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),
- [1]. Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.
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