7-Ethyl-10-hydroxycamptothecin 7-乙基-10-羟基喜树碱
CAS 86639-52-3 MFCD00871873
化学结构图
SMILES: CC[C@@]1(O)C(=O)OCC2C(=O)N3CC4C(=NC5C=CC(O)=CC=5C=4CC)C3=CC1=2
化学属性
| Mol. Formula | C22H20N2O5 |
|---|---|
| Mol. Weight | 392 |
| Melting Point | 217 |
别名和识别编码
| Chemical Name | 7-Ethyl-10-hydroxycamptothecin |
|---|---|
| CAS Number | 86639-52-3 |
| Synonym | (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione 10-Hydroxy-7-ethylcamptothecin 7-Ethyl-10-hydroxycamptothecin 7-Ethyl-10-hydroxycamptothecin, NK012 SN-38 |
| MDL Number | MFCD00871873 |
| Beilstein Registry Number | 4829984 |
| Chemical Name Translation | 7-乙基-10-羟基喜树碱 |
| Reaxys-RN | 4829984 |
| PubChem Substance ID | 87559919 |
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信息真实价格透明
资金保障
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现货库存
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分类
- {SNA} Antitumor Agents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, R to Z, Topoisomerase I, 生化试剂, 癌症研究, 细胞生物学, 酶、抑制剂和底物
- {SNA} Alcohols, Amines, Building Blocks, C11 to C30+, C20 to C30+, C22 to C40+, C9 to C20+, Chemical Synthesis, Ethers, Nitrogen Compounds, Organic Building Blocks, Oxygen Compounds, Phenols
- Alcohols, Amines, Building Blocks, C11 to C30+, C17 to C40+, C20 to C60
产品应用
- A metabolite of Irinotecan, a DNA topoisomerase inhibitor.
相关文献及参考
- Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000),
- Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003),
- Ashley, G., et al.: J. Antibiot., 57, 224 (2004),
安全信息
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P301+P310+P330
- P302+P352+P312+P361+P364
- P304+P340+P311
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- R25 Toxic if swallowed 吞咽有毒
- H301+H311+H331
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