Eremomycin

CAS 110865-90-2 MFCD00874298

化学结构图

110865-90-2
SMILES: CC(C)CC(NC)C(=O)NC1C(O)C2=CC=C(OC3C=C4C=C(OC5=CC=C(C=C5)C(O[C@H]5C[C@](C)(N)[C@@H](O)[C@H](C)O5)C5NC(=O)C(NC(=O)C4NC(=O)C(CC(N)=O)NC1=O)C1C=CC(O)=C(C=1)C1=C(C=C(O)C=C1O)C(NC5=O)C(O)=O)C=3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)(N)[C@@H](O)[C@H](C)O1)C(Cl)=C2

化学属性

Mol. FormulaC73H89ClN10O26
Mol. Weight1558.17

别名和识别编码

Chemical NameEremomycin
Synonym A 82846A
CAS Number110865-90-2
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安全信息

RTECSKD9999900 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - ulceration or bleeding from stomach
   Skin and Appendages - hair
REFERENCE :
   ANKHEW Antibiotiki i Khimioterapiya.  Antibiotics and Chemotherapy. (V/O Me
   zhdunarodnaya Kniga, 113095 Moskow, USSR)  V.33-    1988-
   Volume(issue)/page/year: 34,209,1989

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMBIEH Antibiotiki i Meditsinskaya Biotekhnologiya.  Antibiotics and Medical
   Biotechnology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.30-V.32,
   1985-1987  Volume(issue)/page/year: 32,571,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - necrotic changes
   Skin and Appendages - hair
REFERENCE :
   ANKHEW Antibiotiki i Khimioterapiya.  Antibiotics and Chemotherapy. (V/O Me
   zhdunarodnaya Kniga, 113095 Moskow, USSR)  V.33-    1988-
   Volume(issue)/page/year: 34,209,1989

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1700 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - ulceration or bleeding from stomach
   Skin and Appendages - hair
REFERENCE :
   ANKHEW Antibiotiki i Khimioterapiya.  Antibiotics and Chemotherapy. (V/O

系列性分类

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