Ozagrel Hydrochloride (E)-3-(4((1H-咪唑-1-基)甲基)苯基)丙烯酸盐酸盐
CAS 78712-43-3 MFCD00911569
化学结构图
SMILES: O.Cl.OC(=O)/C=C/C1C=CC(CN2C=NC=C2)=CC=1
化学属性
| Mol. Formula | C13H12N2O2· HCl · xH2O |
|---|---|
| Mol. Weight | 264.71 (anhydrous basis) |
别名和识别编码
| Chemical Name | Ozagrel Hydrochloride |
|---|---|
| Synonym | (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic acid hydrochloride hydrate OKY-046 OKY-046 |
| MDL Number | MFCD00911569 |
| PubChem Substance ID | 24897942 |
| CAS Number | 78712-43-3 |
| Chemical Name Translation | (E)-3-(4((1H-咪唑-1-基)甲基)苯基)丙烯酸盐酸盐 |
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分类
- {SNA} Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Lipids in Cell Signaling, O, Other,
- {SNA} Arachidonic Acid Cascade,
- {SA} Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Lipids in Cell Signaling, O, Other, R to Z, Thromboxane A2 synthase
- {SNA} Arachidonic Acid Cascade,
相关文献及参考
- Merck 14 ,6980
- Shinagawa, K., Participation of thromboxane A2 in the cough response in guinea-pigs: antitussive effect of ozagrel. Br. J. Pharmacol. 131 , 266, (2000) 摘要
- Shirahase, H., Endothelium-dependent relaxation followed by contraction mediated by NK1 receptors in precontracted rabbit intrapulmonary. Br. J. Pharmacol. 129 , 937, (2000) 摘要
- [1]. Max Seidy Saito, et al. Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1591-601.
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