Sc58125 SC58125游离态
CAS 162054-19-5 MFCD00930300
化学结构图
SMILES: CS(=O)(=O)C1C=CC(=CC=1)N1N=C(C=C1C1=CC=C(F)C=C1)C(F)(F)F
化学属性
| Mol. Formula | C17H12N2SO2F4 |
|---|---|
| Mol. Weight | 384.35 |
别名和识别编码
| Chemical Name | Sc58125 |
|---|---|
| CAS Number | 162054-19-5 |
| Synonym | 5-(4-Fluorophenyl)-1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazole 5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)pyrazole SC 58125 SC-58125 |
| MDL Number | MFCD00930300 |
| PubChem Substance ID | 329823724 |
| Chemical Name Translation | SC58125游离态 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclooxygenase, Enzyme Inhibitors, Lipids in Cell Signaling, Pfizer Compounds, S
- Inhibitors
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Cyclooxygenase, Enzyme Inhibitors, Lipids in Cell Signaling, Pfizer Compounds, S, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Heterocycles
- Pharmaceuticals
- Pfizer Compounds
- Intermediates & Fine Chemicals
- Aromatics
产品应用
- SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor with anti-inflammatory properties. SC-58125 blocks edema and hyperalgesia without causing gastric mucosal damage. SC-58125 also displays anti
相关文献及参考
- William, C.S. et al.: Neoplasmia, 3, 428 (2001); Gierse, J.K. et al.: J. Biol. Chem., 271, 15810 (1996); Brideau, C. et al.: Inflamm. Res., 45, 68 (1996);
安全信息
GHS Symbol
- P301+P310
- H301 Toxic if swallowed 吞食有毒
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R25 Toxic if swallowed 吞咽有毒
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