Bevantolol Hydrochloride 盐酸贝凡洛尔

CAS 42864-78-8 MFCD00941389

化学结构图

42864-78-8
SMILES: Cl.CC1C=CC=C(C=1)OCC(O)CNCCC1=CC(OC)=C(C=C1)OC

化学属性

Mol. FormulaC20H27NO4.ClH
Mol. Weight381.94

别名和识别编码

Chemical NameBevantolol Hydrochloride
CAS Number42864-78-8
Synonym CI 775 1-((3,4-Dimethoxyphenethyl)amino)-3-(m-tolyloxy)-2-propanol hydrochloride Sentiloc Ranestol NC 1400 1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol Hydrochloride Bevantolol hydrochloride Cl 775 2-Propanol, 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-, Va Dimethoxyphenethyl)amino]-3-(m-tolyloxy)-2-propanol Hydrochloride
Chemical Name Translation盐酸贝凡洛尔
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Bevantolol is a cardioselective ?-adrenergic blocker. Bevantolol is used as an antianginal, antihypertensive, antiarrhythmic.

相关文献及参考

  • Hoefle, M.L., et al.: J. Med. Chem., 18, 148 (1975),
  • Dukes, I.D., et al.: Br. J. Pharmacol., 84, 365 (1985),
  • Lucas, C.P., et al.: Clin. Ther., 8, 49 (1985),

安全信息

RTECSUB2709000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 419 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCDREP New Cardiovascular Drugs.  (Raven Press, 1185 Ave. of the Americas,
   New York, NY 10036)  1985-  Volume(issue)/page/year: 3,85,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 26,364,1995

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 26,364,1995

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 26,364,1995

系列性分类

相关产品推荐